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Hemochromatosis (he-mo-kro-ma-toe-sis): What Is It?

 

“My mother and I were very close…when she died from hereditary hemochromatosis/ iron overload disease, I was broken hearted…don’t let this happen to anyone in your family …learn how to prevent the symptoms, organ damage and premature death that HH can cause…”

Sandra Thomas, president/founder of the American Hemochromatosis Society (AHS) sits on the bed where her mother died. She is holding dried flowers from her mother’s funeral.

Hereditary hemochromatosis (HH), also known as iron overload disease or "genetic iron poisoning", is the most common genetic disease in the U.S.A. according to the U.S. Centers for Disease Control and Prevention (CDC) in Atlanta, Georgia. One in 8 are "silent carriers" of the single HH gene mutation and 1 in 100-200 have the double mutation putting them at high risk for developing full blown HH. HH can affect men, women and children at any age. Most of the 33 million Americans who have the HH gene mutation don’t know it but it can be diagnosed easily and quickly.

Do you or anyone in your family (living/deceased) have (or have a family history of) these symptoms or risk factors?

  • Arthritis
  • Joint pain/Replacement
  • Diagnosis of Fibromyalgia/Chronic Fatigue Syndrome (CFS)
  • Anemia
  • Hypothyroidism
  • Impotence/Early menopause / Irregular periods
  • Infertility /hysterectomy/no children
  • Diabetes mellitus /High blood sugar
  • Darkening of the skin without exposure to the sun
  • Heart Disease/Heart Attack
  • Stroke
  • Irregular heartbeat
  • bypass surgery
  • Hair loss
  • Weight loss
  • Set off airport metal detectors for no apparent reason
  • Ancestry of Celtic (Irish/Scottish/Welsh) British/Northern European origin
  • Liver disease/hepatitis/cirrhosis/primary liver cancer/elevated liver enzymes
  • enlarged liver/yellow skin & eyes (jaundice)
  • dark urine
  • red palms/Abdominal pain
  • Liver and/or heart transplant.

Ask your medical team for these HH blood tests by name: serum iron, TIBC (total iron binding capacity), and serum ferritin. Danger zone: % saturation greater than > 40% and/or ferritin greater than > 150 ng/mL. Ask for DNA testing by name for the Cys282Y & His63D mutations for both children & adults which will assess genetic risk for HH before damage occurs. Treatment is simple: bloodletting identical to a blood donation.

To learn more call our toll free 24 hour information hotline: 1-888-655-IRON (4766) or send an SASE with three first class stamps to:

AHS
Dept. PSA-Web
4044 W. Lake Mary Blvd.
PMB 416
Lake Mary, FL 32746-2012

 

Josephine Bogie Thomas
April 25, 1921-Mt. Sterling, KY
May 13, 1999-Pittsburgh, PA

 

 

 

 

 

“We all have to die of something, but it doesn’t have to be hereditary hemochromatosis”
Sandra Thomas, AHS President Founder